| Title | Inflammatory bowel disease in patients with celiac disease. |
| Publication Type | Journal Article |
| Year of Publication | 2005 |
| Authors | Yang A, Chen Y, Scherl E, Neugut AI, Bhagat G, Green PHR |
| Journal | Inflamm Bowel Dis |
| Volume | 11 |
| Issue | 6 |
| Pagination | 528-32 |
| Date Published | 2005 Jun |
| ISSN | 1078-0998 |
| Keywords | Adult, Age Factors, Celiac Disease, Cohort Studies, Female, Humans, Inflammatory Bowel Diseases, Male, Middle Aged, Prevalence, Retrospective Studies, Sex Factors |
| Abstract | BACKGROUND: Several case reports and series report an association between celiac disease and inflammatory bowel disease (IBD); however, there is no current data assessing this association. We therefore studied the occurrence of these conditions in a cohort of patients with celiac disease seen at a referral center. METHODS: A database of patients with celiac disease seen between 1981 and 2002 was analyzed. Only biopsy-proven adults were included. Patients who had endoscopic and pathologic evidence of IBD were identified, and their pathology was reviewed. Age- and sex-adjusted prevalence rate ratios were determined by comparing results with population-based prevalence data. RESULTS: Among 455 patients with celiac disease, IBD was identified in 10 (5 had ulcerative colitis and 5 had Crohn's disease). This represented an age- and sex-adjusted prevalence rate ratio for ulcerative colitis of 3.56 (95% confidence interval, 1.48-8.56) and for Crohn's disease of 8.49 (95% confidence interval, 3.53-20.42). CONCLUSION: Within our cohort of patients with celiac disease, IBD was significantly more common than in the general population. |
| Alternate Journal | Inflamm. Bowel Dis. |
| PubMed ID | 15905699 |