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A Diamond in the Rough: IgA-Seq Signatures Stratify New Onset IBD.

TitleA Diamond in the Rough: IgA-Seq Signatures Stratify New Onset IBD.
Publication TypeJournal Article
Year of Publication2021
AuthorsLima S, Longman RS
JournalCell Host Microbe
Volume29
Issue1
Pagination10-12
Date Published2021 01 13
ISSN1934-6069
KeywordsColitis, Diamond, Humans, Immunoglobulin A, Inflammatory Bowel Diseases, Microbiota
Abstract

Intestinal immunoglobulin (Ig)A binds to distinct commensals and pathobionts, but do these IgA-coated bacterial communities define clinical characteristics of inflammatory disease? In this issue of Cell Host & Microbe, Shapiro et al. comprehensively analyze IgA-coated bacteria in new onset inflammatory bowel disease (IBD), revealing their potential in guiding precision therapy and diagnostic stratification.

DOI10.1016/j.chom.2020.12.014
Alternate JournalCell Host Microbe
PubMed ID33444552