Title | A Diamond in the Rough: IgA-Seq Signatures Stratify New Onset IBD. |
Publication Type | Journal Article |
Year of Publication | 2021 |
Authors | Lima S, Longman RS |
Journal | Cell Host Microbe |
Volume | 29 |
Issue | 1 |
Pagination | 10-12 |
Date Published | 2021 01 13 |
ISSN | 1934-6069 |
Keywords | Colitis, Diamond, Humans, Immunoglobulin A, Inflammatory Bowel Diseases, Microbiota |
Abstract | Intestinal immunoglobulin (Ig)A binds to distinct commensals and pathobionts, but do these IgA-coated bacterial communities define clinical characteristics of inflammatory disease? In this issue of Cell Host & Microbe, Shapiro et al. comprehensively analyze IgA-coated bacteria in new onset inflammatory bowel disease (IBD), revealing their potential in guiding precision therapy and diagnostic stratification. |
DOI | 10.1016/j.chom.2020.12.014 |
Alternate Journal | Cell Host Microbe |
PubMed ID | 33444552 |