Diagnosis and classification of ileal pouch disorders: consensus guidelines from the International Ileal Pouch Consortium.

TitleDiagnosis and classification of ileal pouch disorders: consensus guidelines from the International Ileal Pouch Consortium.
Publication TypeJournal Article
Year of Publication2021
AuthorsShen B, Kochhar GS, Kariv R, Liu X, Navaneethan U, Rubin DT, Cross RK, Sugita A, D'Hoore A, Schairer J, Farraye FA, Kiran RP, Fleshner P, Rosh J, Shah SA, Chang S, Scherl E, Pardi DS, Schwartz DA, Kotze PG, Bruining DH, Kane SV, Philpott J, Abraham B, Segal J, Sedano R, Kayal M, Bentley-Hibbert S, Tarabar D, El-Hachem S, Sehgal P, McCormick JT, Picoraro JA, Silverberg MS, Bernstein CN, Sandborn WJ, Vermeire S
JournalLancet Gastroenterol Hepatol
Date Published2021 10
KeywordsAdenomatous Polyposis Coli, Anastomotic Leak, Colectomy, Colitis, Ulcerative, Colonic Pouches, Consensus, Disease Progression, Female, Guidelines as Topic, Humans, Male, Middle Aged, Pouchitis, Proctocolectomy, Restorative, Quality of Life

Restorative proctocolectomy with ileal pouch-anal anastomosis is an option for most patients with ulcerative colitis or familial adenomatous polyposis who require colectomy. Although the construction of an ileal pouch substantially improves patients' health-related quality of life, the surgery is, directly or indirectly, associated with various structural, inflammatory, and functional adverse sequelae. Furthermore, the surgical procedure does not completely abolish the risk for neoplasia. Patients with ileal pouches often present with extraintestinal, systemic inflammatory conditions. The International Ileal Pouch Consortium was established to create this consensus document on the diagnosis and classification of ileal pouch disorders using available evidence and the panellists' expertise. In a given individual, the condition of the pouch can change over time. Therefore, close monitoring of the activity and progression of the disease is essential to make accurate modifications in the diagnosis and classification in a timely manner.

Alternate JournalLancet Gastroenterol Hepatol
PubMed ID34416186
Grant ListP30 DK042086 / DK / NIDDK NIH HHS / United States